ITH5 -Emilia Romagna

Innovation Performance Group (2019) : Moderate +

Total population (2019) 4,459,477

Population per km² (2017) 201

Proportion population older 65 year % 23,95%


Emilia-Romagna is a region in the northeast of Italy comprising the historical regions of Emilia and Romagna, it has a population of 4.5 million. It is home to the University of Bologna, which was founded in 1088 and is the oldest university in the world.


The region has a focus on the emerging fields of regenerative and restorative medicine, as well as pharmaceutical and omics sciences and inclusive services and usable technologies for healthy living and active aging.

Emilia-Romagna  is involved in a number of major initiatives in the field of personalised medicine including Hologene, Custom Implants, Italian Infrastructure for Regenerative Medicine, SUPER  HPC and Big Data and Italian Biobanks network.

Is the region looking for international/European/interregional collaboration opportunities? 

Yes - Identification of standard protocols to collect data and support on how to overcome the barriers about privacy regulation.

Membership status

Member ICPerMed? no 

Mountain ? 27% is hilly and 25% mountainous

Member Euregha? yes 

Adriatic-Ionian MacroRegion? yes

InnoStars Region? yes

Northern Sparsely Populated Area (NSPA)? no

PM region according EC? no 

Baltic Sea MacroRegion? no

S3MedTech region? yes 

Danube MacroRegion? no

S3P4PM region? yes 

Alpine MacroRegion? no

Regions4PM region? yes

ERAPerMed? no 

Central Europe? yes

MedTech4Europe? no

Council of European BioRegions (CEBR)? no

1M+Genome initiative? countrylevel member

European Regions Research & Innovation Network (ERRIN)?  yes

Vanguard Initiative? yes

S3ClusSport member? yes

Policy documents


  1. National level: SNSI - National smart specialization

  2. National level: ALISEI applied life science national cluster strategic plan  

Topics covered by policies : Medical research and innovation (-omics, biomarkers, diagnostics, etc.); Specific disease related research;Prediction and prevention; ICT/genomics, health, lifestyle data(infrastructure); Electronic and mobile health solutions; Public awareness, patient participation with respect to Personalised Medicine/Personalised Health

Which disease related research: - Rare diseases, Oncologic, Orthopeadics

Funding programmes or other support measures:

NACE Personalised Medicine/Personalised Health related to Research and Innovation objectives:

C.20 - Chemicals and chemical products; C.21 - Basic   pharmaceutical products and pharmaceutical preparations C.28 - Machinery and   equipment n.e.c.; J.62 - Computer programming, consultancy and related   activities; Q - Human health and social work activities; Q.88 - Social work   activities without accommodation; M - Professional, scientific and technical   activities; P - Education

Scientific domain NABS Personalised   Medicine/Personalised Health related to Research and Innovation: NABS06 - Industrial production and technology;   NABS07 - Health;NABS09 - Education; NABS12 - General advancement of   knowledge: R&D financed from General University Funds (GUF); NABS13 -   General advancement of knowledge: R&D financed from other sources than   GUF; NABS99 - Total R&D appropriations

Policy objective Personalised Medicine/Personalised Healthrelated related to Research and Innovation objectives: D - Digital transformation; E.37 - Advanced manufacturing systems;E.38 - Advanced materials; E.40 - Micro/Nano-electronics; E.41 - Nanotechnology; G.46 - Ageing societies; G.49 - Public health & well-being; G.50 - Public safety & pandemics; H - Service innovation; I.54 - New organisational models & social relations that meet social needs; I.55 - New products or services that meet social needs; I.59 - Social innovation with regard to health, well-being & elder care

Policy document (RIS3): Yes 

Policy document PM@RIS3: Yes

Major initiatives


  1. Hologene 7

  2. Hologene 7 2.0

  3. Custom Implants

  4. IRMI - Italian Infrastructure for Regenerative Medicine

  5. S3P4PM

  6. Medtch4Europe

  7. Reg4PerMed

  8. SUPER HPC and Big Data

  9. Italian Biobanks network 

  10. Collaboration with Piedmont Region

  11. IZSLER Biobanking of Veterinary Resources (BVR)

  12. BIOGEN: Diagnostic and research genetic Biobank 

  13. ROI: Osteogenesis Imperfecta Registry

  14. BIOGEN - Genetic Biobank 

  15. Italian registry of skeletal dysplasia 

  16. Biorepository of tissue and blood samples, lymphocytes and DNA from patients affected by solitary/multiple osteochondroma and peripheral chondrosarcoma 

  17. Biological Resource Center IRST

  18. Brisighella Heart Study Biobank 

  19. LTTA Biobank (Laboratory for Advanced Therapy Technologies) 

  20. Genetic Biobank 

  21. Tumor Skeletal Tumor Biobank 

  22. REM: Multiple Osteochondromas Registry

  23. Digital Innovation Hubs:


Is the region represented in: Horizon2020; Regional Smart Specialisation Strategy Platforms/Partnerships (RIS3); EIT Health/InnoStars/Regional Innovation Scheme (RIS); other?

  1. BBMRI  EUS3 Platform - Personalized Medicine

  2. H2020 - SMEINST - Oncosmart - ONCOlogic patient profiling and personalized treatment through SMART bedside diagnostics

  3. H2020- SMEINST- BIOFOSTE - Clinical validation of a BIOmarker panel For OSTEoarthritis diagnosis: BIOFOSTE

  4. H2020 - SC1- ADIPOA2 - Clinical trial of autologous adipose-derived mesenchymal stromal cells (ASC) in the treatment of mild to moderate osteoarthritis

Self evaluation

General perception of the implementation level of PM in the region - High

Rate of the need for developing and implementing PM in the region - High

Rate of the need for increasing support/funding for PM activities in the  region - Very High

Rate of the need for increasing the capacity of PM skills in the region - High

Rate of the genomics literacy of the citizens in the region - Medium

Rate of the need for increasing interregional collaboration in PM -  Medium



European Regional and Local Health Authorities (EUREGHA)

European Regions Research and Innovation Network (ERRIN)

Image attribution

By TUBS - Own workThis SVG map includes elements that have been taken or adapted from this map:  Italy location map.svg (by NordNordWest)., CC BY-SA 3.0,

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This project has received funding from the European Union’s Horizon 

2020 research and innovation programme under grant agreement No 825046

The project is co-ordinated by Department Economy, Science and Innovation (EWI) of the Flemish Government.

Department Economy, Science and Innovation - Koning Albert II-laan 35 1030 Brussels, Belgium